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      P63-α (3F11) Mouse mAb
      
				
      Catalog No. :  EM1404
      
				
				
      
				
			
      

			
      
				
      
					
						
      
							规格
							价格
						
      
					      
					
												
      
							50µl
							￥1280
						
      
																		
      
							100µl
							￥1980
						
      
																	      
				
      
			
      
		
      
		
		
      
			
      Overview
      
																					
      

      Product name：
P63-α (3F11) Mouse mAb

      

      Source：
Mouse 

      

      Applications：
WB, IHC

      

      Species reactivity：
Human,Rat,Mouse

      

      Recommended dilutions：
WB 1:1,000-2,000   IHC:1;100-1:200

      

      Immunogen：
Synthetic Peptide

      

      Specificity：
Human

      

      Storage：
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Store at -20°C. Avoid repeated freeze-thaw cycles.

      

      Clonality：
Monoclonal

      

      Isotype：
IgG1

      

      Concentration：
1mg/ml

      

      Observed band：
50-80kDa

      

      GeneID（Human）：
8626

      

      Human Swiss-Prot No.：
Q9H3D4

      

      Cellular localization：
Nucleus

      

      Alternative Names：
N/A

      

      Background：
 p63 can induce p53-responsive genes and apoptosis, mutation of p63 rarely results in tumors . Research investigators frequently observe amplification of the p63 gene in squamous cell carcinomas of the lung, head and neck . The p63 gene contains an alternative transcription initiation site that yields a 40 kDa δNp63 lacking the transactivation domain, and alternative splicing at the carboxy-terminus yields the α, β, and γ isoforms .

      

      
					
      
				
      
			
        
								
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        Western blot analysis of 1) A431 Cell Lysate, 2) 3T3 Cell Lysate , 3) PC-12 Cell Lysate using P63-α（EM1404）Mouse mAb diluted at 1:2000.
        
				
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         Immunohistochemical analysis of paraffin-embedded Human Prostate Tissue using P63-α（EM1404）Mouse mAb diluted at 1:200.
        
				
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         Immunohistochemical analysis of paraffin-embedded Human Prostate Tissue using P63-α（EM1404）Mouse mAb diluted at 1:200.
        
				
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